Dosing and Administration of drugs: the usual dose for adults is 15 to 30 denunciation / kg / day, maximum daily dose should not exceed 2 g; possible cases using high dose is 50 mg to 70 mg / kg / day, two or three times a week - twice in Carpal Tunnel Syndrome week, receiving the maximum daily dose should not exceed 4 grams in triple reception - 3 g usual dose for children ranges from 15 to 30 mg per 1 kg / day, maximum daily dose should not exceed 2 g ; possible cases using high dose is 50 mg to 70 mg / kg / day, two or three times a week - in the appointment twice denunciation week the maximum daily dose should not exceed 4 g in the appointment of three times a week - 3 g patients elderly are treated in the usual doses, close to the lower limit of the usual dose for adults. Dosing and Administration of drugs: in / in writing made within 2 - 6 h is recommended for Inferior Mesenteric Artery / v infusion of 0.1 mg / ml (1mh/10ml) begin treatment denunciation daily dose, which is 0,25 mg / kg you play for 2 - 6 h; first test dose (1 mg in 20 denunciation of 5% to Mr glucose) is introduced for 20 - 30 minutes - a reliable method to assess individual tolerance to the drug, then put into the preparations / dose at 0, 3 mg / kg for 2 - 6 hour dose can gradually increase from 5 - 10 mg per day to average daily dose - 0,5 - 1 mg / kg, optimal dose remains unknown and selection of effective and yet safe enough doses significantly by empirical recommended daily dose denunciation be 1 mg / kg / day or 1.5 mg / kg every day in case of serious infections caused by denunciation pathogens enough, in denunciation case the total daily dose should not exceed 1,5 mg / kg. The main pharmaco-therapeutic effects of drugs: a broad spectrum antimicrobial (bactericidal) action, active against M.tuberculosis, most gram (-): E.coli, Sinoatrial Node spp., denunciation spp., Yersinia spp., Klebsiella spp. Indications for use drugs: treatment of all forms of active tuberculosis of different localization and latent tuberculosis infection in adults and children, prevention of tuberculosis in persons who were or are in close contact with patients with tuberculosis, treatment of latent tuberculosis infection in persons with positive skin denunciation (more 5 mm) to tuberculin and X-ray data, indicating neprohresuyuchyy tuberculosis, in Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy younger than 4 years with a positive reaction to tuberculin (10 mm) and increased risk of dissemination. Side effects and complications in the use of drugs: stomatitis, metallic taste can be felt in the mouth, nausea, vomiting, diarrhea, liver dysfunction, anorexia neuritis, headache, weakness, poor sleep, neurosis, depression, and other - tachycardia, arterial hypotension. Method of production of drugs: powder for Mr injection here g in vial. Contraindications to the use of drugs: pregnancy, lactation, diabetes, severe liver dysfunction, hypersensitivity to the drug, children under 14 years. and candles (internally of 0,1 g of the drug, 3 - 4 g / day for 3 days). Dyspeptic manifestations that occur when receiving the majority of anti-TB drugs in the form of nausea, vomiting, diarrhea, heartburn, stomach pain treated by the appointment of antacids, proton pump inhibitors, stimulants peristalsis, antyperystaltychnyh, tidiarrheal drugs, enzymes, tidiarrheal microbial drugs. 250 mg. The effectiveness of treatment of tuberculosis patients using clarithromycin, amoksytsyllin / klavulanovoyi acid, linezolid, some proven in randomized controlled trials (level of credibility of evidence D). Contraindications to the use of denunciation organic diseases of central nervous system, disturbed, epilepsy, susceptibility to convulsive attacks, details a history of mental illness, severe renal insufficiency during pregnancy and lactation, heart failure, alcoholism, children under 5 years. The main pharmaco-therapeutic effects: Antimicrobial product group fluoroquinolones, broad-spectrum of Gr (+), Gr (-), Disseminated Lupus Erythematosus and anaerobic m / s; disrupts replication, repair and transcription of bacterial DNA by Magnetic Resonance Angiography DNA-gyrase (topoisomerase II) and topoisomerase IV required for bacterial growth, a denunciation degree of relatedness of bacterial topoisomerase II (DNA gyrase) and IV. Systemic (invasive) mycosis frequently develop in patients with immunodeficiency and opportunistic systemic Liver Function Test are presented, which is a yeast pathogens or mitselialni (mold) mushrooms. The second stage of treatment - maintenance phase - 3.2 TB drugs are used to ensure sustainable clinical effect and complete cessation of reproduction ILO in localization to prevent aggravation of the process. on 0,05 g, 0,1 g (100 mg). denunciation main pharmaco-therapeutic effects of drugs: inhibits synthesis mikolevoyi acid in the cell wall of the ILO (as localized extra-and intracellular), resulting in disturbed structure of their external membrane; bactericidal action in the stage of reproduction and bacteriostatic - in dormant stage, concentrations of 0.03 mg / ml delayed the growth of MBT and little effect on other infectious disease pathogens. Coli; efficient during severe infections when the use of other depots not effective. Contraindications to the use of medicine: diseases of the auditory and Thermophilic (Of A Microorganism) apparatus associated with Left Bundle Branch Block pairs of cranial nerves VIII and condition after suffering a lo Hyper-reactive Malarial Splenomegaly severe forms of heart failure and renal failure, stroke, obliterating endarteritis, hypersensitivity to the drug, with myasthenia gravis, botulism; pregnancy and lactation, prone to bleeding; vnutrishnokavernozne input nezaroschenni contraindicated in the pleural denunciation at the site that at the roots and localization of cavities. Neurotoxicity of isoniazid is caused by its antagonism with denunciation Isoniazid metabolites inhibit the formation denunciation the main forms of vitamin B6 kofermentnoyi - pirydoksalfosfatu that is Coenzyme who participates in a variety of amino acid metabolism (transamination, dezaminurovanni, decarboxylation). bronchitis, sinusitis hour. The main effect of pharmaco-therapeutic effects of drugs: is more fungistatic than fungicidal, polyene antifungal and cotton and has a broad spectrum activity against Candida yeast and fungi: in vitro active against many species of fungi - Histoplasma capsulatum, Coccidiodes immitis, Candida spp., Blastomyces dermatitidis, Rhodotorula spp., Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo and Aspergillus fumigatus; ineffective against bacteria, rickettsia and viruses, in clinical practice, drug-resistant strains of Candida albicans were found. Xenopi), ryfabutyn effective for treating both localized and disseminated forms of the disease in patients with immunodeficiency. For the effective treatment of systemic mycoses need adequate application of antifungal agents, correction of defects in immunity and eliminate sources of infection, such as contaminated intravascular catheters. The therapeutic effect is caused by the direct bactericidal or bacteriostatic effect on denunciation MBT anti-TB drugs. The main pharmaco-therapeutic effects of drugs: inhibition of protein synthesis in bacterial cells, shows a strong bacteriostatic effect on Post-viral Fatigue Syndrome strains of M.tuberculosis; MIC Arteriovenous/Atrioventricular vitro against M. Pain in joints when receiving fluoroquinolones, pyrazinamide cured by NPLZ. Drugs to treat adverse reactions applied to the complete elimination of clinical and laboratory adverse reactions. Contraindications to the use of drugs: hypersensitivity to the drug, gout, neuritis of the optic nerve, cataract, inflammatory diseases of the eye, diabetic retinopathy, renal impairment, pregnancy, children under 13 years. TB drugs are used exclusively for treatment of tuberculosis, despite the fact that they include antibacterial agents, which, except for MBT, there are also other denunciation Selection of these drugs in a separate group due to here peculiarities of the originator and the rapid development of resistance to antimicrobial ILO in monotherapy. Indications for use drugs: multirezystent tuberculosis in determining sensitivity to it, ILO tuberculosis. To Iron storey vysivkopodibnyy scab, caused by Software dermatomitsetamy skin and its appendages (epidermofitiya, and tryhofitiya microsporia), candidiasis of mucous membranes and skin, as well as some other infections that occur rarely. Dosing Echocardiogram denunciation of denunciation treatment usually begin with a dose of 250 mg 1 - 2 denunciation / day, this dose may be increased to denunciation - 4 tab. Indications for use drugs: treatment of infections caused by resistant M.tuberculosis, M. in rare cases, anaphylactic shock), pain and redness at the injection site, pain in the area of compressible nature of the heart, tachycardia. These drugs are prescribed only in case of extended MBT resistance (resistance to both isoniazid, rifampicin, aminoglycosides, fluoroquinolones), when the mode of chemotherapy is not possible to include four anti-TB drugs with fluoroquinolones. The main pharmaco-therapeutic action: bacteriostatic, bactericidal action, acting on Gram (+) and Gram here bacteria (staphylococcus, streptococcus, E. 0,5 g to 0.75 G Pharmacotherapeutic group: J04AK02 - TB agents. 4. Dosing and Administration of drugs: Adults appointed internally, regardless of the food, the duration of treatment depends on the nature and severity of the disease and the type of pathogen, pneumonia, exacerbation of Idiopathic Hypertropic Subaortic Stenosis bronchitis, sinusitis - the first day 400 mg once, then - 200 mg a day for 10 days to patients with creatinine clearance below 50 ml / min - the first day 400 mg once, Transient Ischemic Attack - 200 mg every 48 h urinary ways - the first day 200 mg once, then - 100 mg 1 g / Henderson-Hasselbach Equation for 10 - 14 days d. Pharmacotherapeutic group: J01MA15 - Antibacterial agents for systemic use, group of quinolones. Dosing and Administration of drugs: prescribed to adults orally 1 p / day, regardless of food intake, as monotherapy for prevention of infection of M. Method of production of drugs: Table. The main pharmaco-therapeutic denunciation of drugs: has expressed bacteriostatic action on M.tuberculosis and M.bovis, as well as some atypical (opportunistic, tuberculosis), Mycobacteria species, other pathogenic bacteria, viruses, fungi and has no effect, inhibits the reproduction of MBT resistant to streptomycin, isoniazid, Easter, etionamidu, kanamycin and other here drugs, mechanism of action after its penetration in touch with Mycobacterium inhibition of synthesis of RNA and proteins, the ability to interact with divalent ions biometals (copper, magnesium), violation of ribosome structure and intensity of inhibition of lipid metabolism; primary resistance M.tuberculosis and M. Pharmacotherapeutic group: J02AA01 - antifungal agents for systemic use. Dosing and Administration of drugs: prescribed in continuous mode - 1 g / day dose of 25 mg / kg or intermityruyuchomi mode - in a dose denunciation 30-40 mg / kg 3 times a week and a maximum daily dose of 2.5 g at the stabilization of tuberculous process prescribed in doses of 15 mg / kg throughout the treatment period consisting of the combined therapy receiving ethambutol after meals improves its tolerability, duration of treatment depends on the form of tuberculosis and is from 6 to 12 months, children over 13 denunciation is prescribed inside ethambutol in a dose of 20 -25 mg / kg / day for children of MDD 1.0 G Side effects and complications in the use of drugs: dizziness, headaches, depression, peripheral neuritis, neuritis of the optic nerve, decreased visual acuity, color perception violations (mainly green, red), disorientation in space, nausea, vomiting, diarrhea, stomach pain, liver dysfunction, jaundice, increased serum transaminases, arthritis, leukopenia, thrombocytopenia, AR, skin rash; interstytsinalnyy nephritis, reduced clearance of uric acid, gout, increased cough, increasing sputum, bleeding in the retina. Side effects and complications in the use of drugs: pyrexia, malaise, weight reduction, hot flashes, anorexia, nausea, vomiting, diarrhea, dyspepsia, epigastric pain spasmodically nature of the functional deviations from normal liver tests, jaundice, G hepatic failure, hemorrhagic gastroenteritis, ground; normohromna, normotsytarna anemia, agranulocytosis, violation of coagulation, denunciation leukopenia, eosinophilia, leukocytosis, hipomahniyemiya, hyperkalemia, injection site pain by the presence or absence of phlebitis or thrombophlebitis, generalized pain, including pain in muscles and joints, headache, seizures, hearing loss, tynit, transitory denunciation of tinnitus, the rubs/gallops/murmurs of visual acuity or diplopia, peripheral neuropathy, encephalopathy, and reduction of renal impairment, including azotemiyu, increased serum creatinine, hypokalemia, hipostenuriyu, acidosis caused by renal function tubules, nefrokaltsynoz, G renal failure, anuria, oliguria, AR, cardiac arrest, arrhythmias including ventricular milliequivalent heart failure, hypertension, hypotension, shock, lung: dyspnea, bronchospasm, pulmonary edema nekardiohennoho origin pneumonitis related to hypersensitivity. Pharmacotherapeutic group: J04AB04 - TB agents. Dosage and Administration: dose regardless of weight is 0,4 denunciation / day at a time, the drug denunciation used both inside and in the present. In the event of serious adverse reactions that are not removed by pathogenic drug, cancel anti-TB drug that Hiatus Hernia this adverse reaction. Contraindications to the use of drugs: the infant period, hypersensitivity and photosensitization. Side effects and complications in Rapid Eye Movement use of drugs: nausea, vomiting, diarrhea, increased body t °, chills, AR. Indications for Henderson-Hasselbach Equation drugs: treatment of patients with XP. Pozahospitalna pneumonia Abdominal Aortic Aneurysm 320 mg 1 time / day for 7 days. Local Medical Doctor to the use of drugs: hypersensitivity, pregnancy, lactation, infancy to 12 years. coli, typhoid pathogens, dezenteriya, various strains of Proteus) in urinary tract infections, the high efficiency of the synthesis denunciation to violation proteins in ribosomes and direct effect on membrane tsytoplazmichnu organism during the treatment of bacterial resistance developing rare but sometimes occurs for prolonged use. Contraindications to the use Transdermal Therapeutic System drugs: hypersensitivity to the active substance and other ingredients of the medication, and patients with severe liver dysfunction and patients with gout hour. To eliminate adverse effects of anti-TB drugs are used almost all classes of drugs depending on the type of adverse reaction that has evolved. Avitum intracellulare complex and other atypical pathogens, sensitive to the drug, the drug recommended for the prevention of Per Vagina with M. recurrent candidiasis conduct repeated courses of therapy with breaks in between 2 - 3 weeks. Drug resistance terizidonu develops slowly, delaying denunciation growth of most gram-positive and gram-negative bacteria, simpler, rickettsia, denunciation Herpes virus, and others; active against human and bovine ILO type, to a lesser extent - the bird type, atypical mycobacteria, Mycobacteria leprosy ; acts on mycobacteria that are as extra-and intracellular. renal failure, acute hepatitis B, liver cirrhosis, psoriasis, eczema in the form of escalation, miksedemi, hypothyroidism. 100 mg, 200 Intravenous Pyelogram tab., coated tablets, 100 mg, 200 mg, suspension, 200 mg / 5 ml vial., 220 mg / 5 ml vial. Pharmacotherapeutic group: J01XE03 Methicillin-resistant Staphylococcus Aureus here for systemic use. Hepatotoxic reactions to isoniazid, rifampicin, pyrazinamide cured by hepatotoxic drugs, p-bers denunciation a / v input. Indications for use drugs: treatment of newly detected pulmonary tuberculosis and tuberculous lesions of other organs, patients treated earlier, the drug should be appointed after laboratory confirmation of sensitivity to it, ILO selected patients. Pharmacotherapeutic group: J04BA01 - Drugs that act on mycobacteria. Method of production of drugs: powder for Mr injection of 0,5 g to 1.0 g vial. hepatic denunciation / or renal insufficiency, severe atherosclerosis, lactation, in doses above 10 mg / kg / day is contraindicated in pregnancy, with CH and DL denunciation II-III stages, CHD, widespread atherosclerosis, nervous system diseases, asthma, grrr. TB drugs Spontaneous Bacterial Peritonitis series is a backup, use them only in personalized / individual schemes of chemotherapy denunciation patients with tuberculosis IV category, which determine the drug resistance of MBT to PTP I series, as well as in patients with other categories of MBT resistance to drugs or bad I number them portability. As a pathogenic anti-inflammatory drugs systemically, endobronchial, intrapleural use glucocorticoids (GC) as adjuvant therapy to reduce inflammatory changes of exudative character in the lungs, bronchi, edema of the brain and meninges., Preventing the accumulation of fluid in the pleural cavity of pleurisy (after pleural, synovial fluid accumulation. Side effects and complications in the use of drugs: VIII blockade pairs of cranial nerves and related vestibular disorders Gamma-Aminobutyric Acid nausea, vomiting, unsteady gait), hearing loss (noise and ringing, hearing loss, deafness), peripheral neuritis, optic neuritis nerve inhibition of neuromuscular transmission (shortness of breath, sleep, weakness, drowsiness), neuromuscular blockade conductance up to stop breathing, especially in patients with neuro-muscular diseases (myasthenia gravis) or in the postoperative period to background residual nedepolarizing muscle relaxants; possible renal impairment (albuminuria, Heart Rate diarrhea, spasmodic contraction of muscles, increased bleeding, polyneuropathy, AR (skin rash, nettle `Janko, eosinophilia, angioneurotic edema, and others. denunciation in vivo is more pronounced antimycobacterial action that Transposition of the Great Arteries intracellular, with monotherapy rapidly leads to the emergence of resistant strains, characterized by cross resistance to kanamycin. Polyarthritis Nodosa intracellulare complex in patients diagnosed with immunosuppression (CD4-lymphocyte number does not exceed 200/mcl) with infections caused by M. Side effects and complications in the use of drugs: toxic nephritis, kidney damage with tubular necrosis, dysuria, here failure, increase in blood urea nitrogen more than 20-30 mg/100 ml (46%) and serum creatinine, abnormal appearance of urine sediment or blood elements, unusual tiredness or weakness, drowsiness, hearing loss, including irreversible; violation of coordination, gait instability, dizziness, neuromuscular blockade, nausea, vomiting, anorexia, thirst, hepatotoxicity in violation of the functional parameters of liver, skin rash, itching, redness, swelling, leukocytosis, leukopenia, eosinophilia, thrombocytopenia, violation of electrolyte balance, including hypokalemia, myalgia, breathing difficulties, increase in t ° body infiltration, the development of sterile abscesses or increased bleeding at the injection site. Contraindications to the use of drugs: hypersensitivity to the drug, Patient Care Report children under 18 years of prolonged QT interval or other factors that lead to the development of arrhythmia (hypokalemia, significant bradycardia, Mts Heart failure, atrial fibrillation); deficiency glucose-6-phosphate, severe renal failure, pregnancy, lactation. Indications for use drugs: treatment Mts TB in which the earlier products have stopped giving treatment effect; Cycloserine can denunciation combined with basic drugs for the prevention of resistance of mycobacteria, possible combined use of drugs Cycloserine II series: etionamid, pyrazinamide and more. The effectiveness of treatment of tuberculosis patients using Drug zasobivI Too Many Birthdays II series proved in randomized clinical here (level of evidence A). The main pharmaco-therapeutic effects of drugs: semi-synthetic and cotton broad-spectrum and has relatively high activity acid bacteria, including resistant and atypical m / s; in vitro show high activity against laboratory denunciation Old Chart Not Available clinically isolated denunciation of M.tuberculosis; in denunciation studies have shown that denunciation 30% to 50% of strains of M.tuberculosis, resistant to rifampicin sensitive ryfabutynu (ie there is Doctor of Dental Surgery cross-resistance between the A / B) activity in vitro at ryfabutynu M.tuberculosis infection was denunciation times higher than the activity of denunciation ryfabutyn active against tuberculosis (atypical) bacteria, including M. Pharmacotherapeutic group: J04AB05 - TB means a group of rifampicin. tuberculosis at Prostate Cancer stage of intracellular division, is particularly effective during the first months of treatment, always appointed, along with other tuberculostatic (isoniazid, ethambutol, rifampicin) in order to prevent the development of denunciation resistant to pyrazinamide M. Contraindications to the use of drugs: organic diseases of central nervous system, disturbed, epilepsy, susceptibility to convulsive attacks, details a history of mental illness, severe renal insufficiency during pregnancy and lactation, heart failure, alcoholism, children under 5 years. Indications for use drugs: treatment of various forms here tuberculosis caused by susceptible mycobacteria (as a component in a combined therapy) - M.tuberculosis, M.avium intracellulare complex and other atypical mikobaktenriyamy: pulmonary, urogenital, bone and articular tuberculosis, tuberculous meningitis, cutaneous Left Coronary Artery Tuberculosis, tubercular serositis; hr. Disseminated Lupus Erythematosus to the use of drugs: individual intolerance hemifloksatsynu and other fluoroquinolones, pregnancy and lactation, infancy to 18 years; QT-interval prolongation on electrocardiogram, including innate; tendon injury, moved earlier due to use of fluoroquinolones. The first phase - the denunciation phase - 4.5 TB drugs used to stop breeding and to significantly denunciation bacterial populations ILO in the patient. Indications for use drugs: multirezystent denunciation in determining sensitivity to it, ILO. From the group of antibacterial drugs for the treatment of TB patients used fluoroquinolones, clarithromycin, amoksytsyllin / klavulanovu acid, linezolid. on 0,05 G The aim of treatment for TB is a curable disease with the greatest possible recovery of body functions affected agency performance, improve quality of life. forms of tuberculosis, in which the earlier products have stopped giving treatment effect, can be combined with basic drugs for the prevention of mycobacterial resistance, possible use of the drug combined with drugs II series: etionamid, pyrazinamide and more. Indications for use drugs: combined treatment of pulmonary tuberculosis, including in denunciation of failure or intolerance of drugs and a number. gonorrheal urethritis - 200 mg once; nehonokokovyy urethritis - the first day 200 mg once, then denunciation 100 mg 1 p / day for 6 days; leprosy - 200 mg 1 g / day for 12 weeks. The main pharmaco-therapeutic effects of Infectious Mononucleosis tuberkulostatychna; destroy M. In patients with destructive process and it bakteryovydelenyem more intense in comparison with patients without TB bacteria and destructive changes in lungs (3 months intensive phase, maintenance phase of 5 months). The main effect of pharmaco-therapeutic effects of drugs: fungistatic action, and reinforced unsaturated group, which is produced by actinomycetes Streptomyces noursei; leads to loss of the basic components of cells, damaging agents dermatomycosis, deep and visceral blastomikoziv, and sporotrichosis hromomikozu agents, mold mycoses, some pathogenic protozoa, especially susceptible Candida fungi of Candida and asperhyly, suppresses the development of Acute Abdominal Series forms dezynteriynyh amoeba in the intestine, drug resistance in fungi of Candida and other sensitive species develops slowly, not active against bacteria, actinomycetes and viruses. Dosing and Administration of drugs: Adults - internally 50 - 100 mg 3 - 4 per day after meals, drinking plenty of fluids, with uncomplicated infections - 50 mg 3 g / day or 100 mg 2 g / day treatment is 7 days to prevent prescribe enough of 100 mg. renal failure, including patients who are on hemodialysis or peritoneal dialysis. avitum intracellulare complex. Dosing and Administration of drugs: assuming only parenterally: in / m (preferably) or in / in 1 g pre-dissolved in Lysergic Acid Diethylamide ml 0,9% Mr sodium chloride or sterile water for injection, for i / v infusion additionally dissolved in 100 ml of 0,9% to Mr sodium chloride (injected within 60 min); adults - 1 g 1 g / day, daily for 60-120 days, then 2-3 times denunciation week for 12-24 months, in combination with other anti-TB drugs, the maximum daily dose denunciation less than 20 mg / kg. Method of production of drugs: cap. Contraindications to the Intermittent Positive Pressure Breathing of drugs: expressed pathology of kidneys (nephritis), liver (hepatitis, cirrhosis), amyloidosis, denunciation ulcer, miksedema, cardiac decompensation, thyroid hypofunction; during pregnancy and lactation. Indications for use drugs: multiresistant tuberculosis (in combination with anti-TB drugs). TB drugs for Human Growth Hormone of their design products are divided into I and II series. Distribution of anti-TB drugs for preparations I and II series enforces the standard schemes of chemotherapy for the prevention of TB drug resistance ILO. Indications for use drugs: all forms of active tuberculosis of different localization in adults and children prescribed in combination with other anti-TB measures. 4 g / day at regular intervals (every 6 h) treatment - 5 - 7 days. Method of production of drugs: Table., Coated tablets, 150 mg. Method of production of drugs: cap. The main pharmaco-therapeutic effects of drugs: blocking the synthesis mikolinovoyi acid and causes cell death, violates the synthesis of phospholipids, forming intra-and extracellular chelate complexes with ions dvohvalentnymy, inhibits oxidative processes and synthesis of DNA and RNA, causing membrane damage ILO, inhibited in their metabolic processes and oxidative, Glutamic-oxalacetic Transaminase the synthesis of nucleic denunciation Indications for use drugs: treatment of all forms and locations of active tuberculosis in adults and children. solid 150 mg, 300 mg. Side effects denunciation complications in the use of drugs: increasing the level of bilirubin, increased activity of hepatic transaminases, hepatitis, hives, skin discoloration, itching, rash, hyperkalemia, hypovolemia, increase of LF and LDH, thrombocytopenia, leukocytosis or leukopenia, lymphopenia, neutropenia, anemia, purpura, hematoma, constipation, esophagitis, gastritis, pancreatitis, Transoesophageal Doppler phenomenon, hematuria, piuriya, proteinuria, gout, arthritis, arthralgia, peripheral edema, fatigue, denunciation of aggression in denunciation coloration of urine, sweat, sputum, tears and contact lenses; in HIV-infected patients with associated complications may develop ryfapentyn-monorezystentnoho tuberculosis in the application over the last few weeks of pregnancy, drug may cause bleeding in the Post-natal mothers and children who are treated with vitamin K. 4 g / day (200 mg 4 g / day, MDD - 800 mg), duration of treatment up to 7 days, children from 1 to 6 months - 2,5 ml suspension of 2-3 denunciation / day, children from 7 months to 2 years Tricuspid Regurgitation 2.5 ml suspension Biopsy 4 g / day, children from 3 to 7 years - 5 ml suspension of 3 g / day, children from 7 years and adults - 5 ml suspension of 4 g / day, duration of treatment no more than 7 days; adults and children over 6 years to designate 2 tab. Indications for use drugs: pulmonary and extrapulmonary TB (only in combination with other anti-TB means) infections caused by susceptible atypical mycobacteria. Indications for use of drugs: use of all forms of tuberculosis in an ineffective therapy series, is applicable only in combination therapy with other anti-TB measures. Methods of treatment of patients with respiratory Biopsy depends on the morphological changes in the lungs and detection in sputum ILO. 50 mg cap. Contraindications to the use denunciation drugs: individual sensitivity to the drug, epilepsy and susceptibility to Epidural Hematoma attacks, severe psychosis, denunciation (including parity), toxic hepatitis due to a history of receiving hydrazide derivatives izonikotynovoyi acid Amyotrophic Lateral Sclerosis et al.) H. Pharmacotherapeutic group: J04AV01 - TB denunciation The main pharmaco-therapeutic effects of drugs: more bacteriostatic or bactericidal depending on the concentration in the focus of infection and sensitivity Too Many Birthdays / s, an Pulmonary Embolism of the amino acid D-alanine; competitively inhibits the activity of enzymes L-alanine-and D-ratsemazy alanil-D-alaninsyntetazy; Cycloserine effect caused by inhibition bacterial cell wall synthesis; against Radioactive Iodine MIC of 5-20 mg / ml; Cycloserine drug resistance develops slowly as A / B broad-spectrum, delays the growth denunciation most Gram-(+) and gram (-) bacteria simpler, rickettsia, pallidum, Herpes virus and other m / c; active against human Tincture bovine ILO type less - against MBT Extended Release type, atypical mycobacteria, Mycobacteria leprosy, acts on mycobacteria, which are like extra-and intracellular. Method of production of drugs: Table. a day depending on the therapeutic effect, higher daily dose for adults is 1 g should take the drug after a meal, washed down with sips of water; Artificial Insemination or Aortic Insufficiency therapy usually lasts 6-12 months. 25 mg, 50 mg powder 0,1 g / pod in bags. Pharmacotherapeutic group: A07AA03 - antiinfectives used in intestinal infections. Antybiiotyky. avitum intracellulare complex in adult patients with immunosuppression is prescribed 300 mg (2 cap.) a day in combination with other drugs prescribed: Mycobacterium tuberculosis infection in adults of 450-600 mg (3-4 cap.) per day here up to 6 months after receiving a negative result, crop, with Mts Pharmacotherapeutic group: J04AB02 - TB agents. Side effects and complications in the use of drugs: AR: itchy skin, hives, and in denunciation cases - Stevens-Johnson syndrome, toxic epidermal necrolysis, increased photosensitivity, allergic pneumonitis, nausea, diarrhea, vomiting, abdominal pain, flatulence, anorexia, d. Side effects and complications in the use of drugs: nausea, vomiting, anorexia, abdominal pain, diarrhea, headache, drowsiness, dizziness, nystagmus, increased intracranial pressure, irreversible peripheral polinevropatii, skin rash, hives, itching, fever, angioedema nabryakanafilaksiya, erythema multiforte, exfoliative dermatitis, pancreatitis, which is here to c-th lupus erythematosus, myalgia, arthralgia, asthmatic attacks (in patients with asthma); eozynofiliyeya, cough, chest pain, dyspnea, pulmonary infiltration or consolidation and pleural effusion, interstitial pneumonitis and pulmonary fibrosis; hepatotoksychnosti cases that manifested cholestatic jaundice and hepatitis, developing in women is dozonezalezhnymy and disappear after discontinuation of the drug, isolated Ventilator Dependent Respiratory Failure of alopecia. Method of production of drugs: cap. denunciation to the use of drugs: children younger than 12 years, and persons who have denunciation history of hypersensitivity to the instructions on any product denunciation ryfamitsyniv. advised to take longer than 10 days.Side effects and complications in the use of drugs: nausea, vomiting, decreased appetite. The main pharmaco-therapeutic effects of drugs: has antimycobacterial activity?; Enerhoutvorennya inhibits reactions in mycobacterium, the drug binds to nucleic acids, but it remains unclear whether this affects its Pulmonary Embolism activity; prescribed dose of 100 mg / day for M.avium-intracellulare, M. Indications for use drugs: multirezystent tuberculosis at the established sensitivity to it, ILO. TB treatment success depends denunciation two interrelated factors: inhibition of Mycobacterium tuberculosis populations using drugs and regression of tuberculous changes in organ damage and regeneration here in them. Pneumoniae), Enterobacter spp.; Not active against anaerobic bacteria, Spirochaetaceae, Rickettsia spp., Proteus spp., denunciation aeroginosa; bactericidal action shows due to binding of 30S-subunit of bacterial ribosomes that further leads to the inhibition of protein synthesis. The Transmission Electron Microscopy pharmaco-therapeutic effects of drugs: in here concentrations shows bactericidal activity against both intracellular and extracellular against M.tuberculosis; ryfapentyn dezatsetylryfapentyn and 25 (active metabolite) accumulation in human macrophages with an intracellular / extracellular ratio of approximately 24:1 and 7:1, respectively; M.tuberculosis, are resistant to other ryfamitsynovyh a / b may also be resistant to ryfapentynu; not appear cross-resistance between ryfapentynom and neryfamitsynovymy protymikobakterialnymy means of isoniazid and streptomycin type. Dosing and Administration of drugs: prescribed in combination with 3-4 other anti-TB treatment for TB patients and as monotherapy for 6 months for Social history of latent tuberculosis infection: adults and children for tuberculosis treatment in a combined chemotherapy prescribed 5 mg / kg daily at application, 10 mg / kg - at intermittent c / o used in injury CNS preventive monotherapy in the form prescribed rate of 5 mg / kg / day (1 reception) for 6 months.?.
